Pencil Beam Scanning in Patients With Renal Tumors

Introduction

• Org Study ID: 17-014386
• NTC ID: NCT03810651
• Lead Sponsor Name: Children's Hospital of Philadelphia

Overall Status

Conditions

• Renal Sarcoma
• Wilms Tumor

Brief Summary

This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.

Eligibility Criteria

Inclusion Criteria:

Less than 30 years of age

Diagnosis

a. Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care including

Any patient with favorable histology (FH), stage III disease
Any patient with focal or diffuse anaplasia
Any patient with CCSK
The patient is a candidate for external beam radiotherapy based on standard of care for treatment of Wilms tumor or CCSK

Exclusion Criteria:

Prior radiotherapy to the region of the study cancer
Chemotherapy administered for diagnosis of Wilms tumor or CCSK
Pregnant or breastfeeding