Pencil Beam Scanning in Patients With Renal Tumors

Introduction

• Org Study ID: 17-014386
• NTC ID: NCT03810651
• Lead Sponsor Name: Children's Hospital of Philadelphia
• Status: RECRUITING

Conditions

• Renal Sarcoma
• Wilms Tumor

Brief Summary

This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.

Eligibility Criteria

Inclusion Criteria:

* Less than 30 years of age
* Diagnosis

a. Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care including
1. Any patient with favorable histology (FH), stage III disease
2. Any patient with focal or diffuse anaplasia
3. Any patient with CCSK
* The patient is a candidate for external beam radiotherapy based on standard of care for treatment of Wilms tumor or CCSK

Exclusion Criteria:

* Prior radiotherapy to the region of the study cancer
* Chemotherapy administered for diagnosis of Wilms tumor or CCSK
* Pregnant or breastfeeding