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Kidney cancer can impact children and adolescents, resulting in not only reduced life expectancy but also painful and distressing long- and short-term effects on their physical and emotional well-being. The Kidney Cancer Association wants to change that. This Childhood Cancer Awareness Month, the KCA is committed to creating awareness and raising funds for research to find a cure. Donate and invest in research!

Kidney cancer is one of the most common types of childhood cancer

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Childhood Cancer

The most common types of childhood cancers include kidney cancers, leukemias, brain tumors, lymphomas, neuroblastomas, and sarcomas.

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The exact causes of most childhood cancers are not well understood, but genetic factors, environmental exposures, and sometimes specific genetic syndromes can play a role.

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Treatment for childhood cancers often includes a combination of surgery, chemotherapy, radiation therapy, targeted therapy, and in some cases, stem cell transplantation.

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Global Impact

Childhood cancer is a global health concern, and efforts to improve diagnosis, treatment, and support for affected children and families extend across the world.

These are some of the kidney cancer types most often found in children and be discovered as young as infancy. Learn more about these kidney cancer types through our Affiliate Partners:

Translocation RCC

Translocation RCC is subtype of kidney cancer characterized by genetic changes involving translocations of genetic material between chromosomes. This can affect young children and currently has no standard treatment protocol. Learn more at Joey’s Wings Foundation, named in memory of Joey Xu who died of translocation RCC at age 10.

Wilms Tumor

Wilms tumor, also known as nephroblastoma, is a type of kidney cancer that primarily affects children. It is one of the most common types of kidney tumors found in children and is usually diagnosed before the age of 5. Learn more at the Wilms Cancer Foundation.

Hereditary Leiomymatosis and Renal Cell Cancer (HLRCC)

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a genetic condition that affects multiple organs, including the skin, uterus, and kidneys. HLRCC is caused by mutations in the FH gene and is often first recognized when individuals develop cutaneous leiomyomas (benign skin tumors) or when they present with symptoms related to uterine fibroids or kidney tumors. This can become present in young children and adolescents, which can then lead to an aggressive form of kidney cancer. Learn more at the HLRCC Foundation.

Renal Medullary Carcinoma

Renal Medullary Carcinoma (RMC) is an extremely aggressive form of kidney cancer that primarily affects adolescents and young adults, with some individuals being as young as 8 years old. RMC predominantly affects individuals with sickle hemoglobinopathies such as sickle cell trait and disproportionately affects African American males mroe than females. RMC is characterized by its rapid growth, high propensity for metastasis (spreading to other parts of the body), and resistance to traditional cancer treatments. Learn more at the Chris “CJ” Johnson Foundation.

In Partnership With Our Affiliates