Understanding Your Report

Below is an example of a pathology report someone diagnosed with kidney cancer may receive. Hover over a section to learn more about that part of the report.

Clinical History: Patient is a 48-year-old African American male who presented with hematuria. Abdominal/pelvic CT showed a large right renal mass.

Specimen: Right kidney

Diagnosis:

  1. RIGHT KIDNEY, RADICAL NEPHRECTOMY:
  • Clear cell renal carcinoma
  • See comment and synoptic report

Comments:

Immunohistochemical stains show positive staining in tumor cells for PAX8, CA9, and AE1- AE3. Cathepsin K and CK7 are negative in tumor cells. The findings support the diagnosis.  

Synoptic Diagnosis:

  1. RIGHT KIDNEY:

SPECIMEN

Procedure:

Radical nephrectomy

Specimen Laterality:

Right

Tumor Focality:

Unifocal

Tumor Site:

Perinephric fat

Tumor Size:

Greatest Dimension (Centimeters): 4.5 cm

Histologic Type:

Clear cell renal cell carcinoma

Histologic Grade (WHO/ ISUP)

G3 (Nucleoli conspicuous and eosinophilic at 100x magnification)

Tumor Extent:

No extension into other organ(s)/structure(s)

Sarcomatoid Features:

Not identified

Rhabdoid Features:

Not identified

Tumor Necrosis:

Not identified

MARGINS

Margin Status: 

All margins negative for invasive carcinoma

REGIONAL LYMPH NODES

Regional Lymph Node Status: 

Not applicable (no regional lymph nodes submitted or found)

PATHOLOGIC STAGE CLASSIFICATION

Primary Tumor (pT):  

pT4

Regional Lymph Nodes: (pN): 

pN not assigned (no nodes submitted or found)

Gross description

RIGHT KIDNEY

Received fresh-labeled with the patient’s identification and “Right kidney”, is a right nephrectomy specimen with attached perinephric fat. The kidney is 9.7 x 5.8 x 3.5. The attached 8 x 0.5 segment of ureter is grossly unremarkable, as are the renal vessels. The external surface is marked with blue ink.

The kidney is bivalved to reveal a 4.5 x 3.8 x 3.2 cm yellow-orange solid mass in the superior perinephric fat. The mass is adherent to the superior portion of the renal capsule but not grossly appear to be originating from the renal parenchyma. The mass is 6.5 cm from the ureter margin, 1.2 cm from the renal artery, and 2.0 cm from the renal vein. No other grossly distinct massesor nodules are seen. The remaining kidney is pale tan, with a well defined corticomedullary junction, and a cortical thickness of 0.4 cm.

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Keep Learning:

The Kidney Cancer Association provides educational literature for anyone impacted by kidney cancer.